Someone once called me "cute as a mole-rat," and I thanked them for the complement. Then I found out what mole-rats looked like, and I cried in the shower for a few days.
But I shouldn't have been so hasty to dismiss my homely likeness: The African naked mole-rat is immune to certain types of pain.They respond to mechanical pain like pinching, but don't respond to pain caused by capsaicin (the hot element in chili peppers), hot objects, and even burns from acid.
Thomas Park of the University of Illinois at Chicago, Gary Lewin at the Max-Delbrück Center for Molecular Medicine in Berlin, Germany, and their colleagues discovered that mole-rats lack substance P, a compound that transmits information relating to chronic pain in between nerve cells. The team hopes to apply this discovery in gene therapy to help humans who suffer from chronic pain.
“Instead of going to the pain region of the spinal cord as we would expect, the nerves that lead from acid and capsaicin sensors go to the touch region,” says Park. “And their nerve fibres do not respond to acid at all.”
Did you hear that? At all.
Continue reading 'Mole-rats can't feel certain types of pain, still 'pretty on the inside'' >
